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Chỉ định và Liều dùng
Otic/Aural
Otitis externa Adult: 1 spray (60 mg) to each affected ear tid. Continue treatment until 2 days after symptoms have disappeared. Discontinue if there is no clinical improvement after 7 days.
Child: ≥2 yr Same as adult dose. |
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Chống chỉ định
Hypersensitivity to neomycin sulfate, dexamethasone or glacial acetic acid. Known or suspected perforation of tympanic membrane or where a tympanostomy tube (grommet) is in situ.
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Thận trọng
Childn. Pregnancy and lactation.
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Tác dụng không mong muốn
Skin sensitisation or hypersensitivity leading to burning, stinging, irritation, itching and dermatitis.
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Tác dụng
Description:
Mechanism of Action: Neomycin is a broad spectrum antibiotic while dexamethasone is a topical anti-inflammatory steroid. Acetic acid assist in the control of bacterial infection by producing a low pH. Pharmacokinetics: Distribution: Widely distributed in the surface. |
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Đặc tính
 Source: National Center for Biotechnology Information. PubChem Database. Neomycin, CID=8378, https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin (accessed on Jan. 21, 2020)  Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 5743, Dexamethasone. https://pubchem.ncbi.nlm.nih.gov/compound/Dexamethasone. Accessed Aug. 25, 2023.  Source: National Center for Biotechnology Information. PubChem Database. Acetic acid, CID=176, https://pubchem.ncbi.nlm.nih.gov/compound/Acetic-acid (accessed on Jan. 22, 2020) |
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Bảo quản
Store at or below 25°C. Do not freeze.
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Phân loại MIMS
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Tài liệu tham khảo
Joint Formulary Committee. Dexamethasone with Glacial Acetic Acid and Neomycin Sulfate . British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 06/04/2016. Otomize (Forest Laboratories UK Limited). MHRA. https://products.mhra.gov.uk/
. Accessed 06/04/2016.
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